Zanzibar, originally the name of an ancient island state on Earth, may refer to:
- the Zanzibar System, a star system near Manticore.
- the planet Zanzibar in the eponymous system.
- the Caliphate of Zanzibar, a star nation in the eponymous system.
- the Zanzibar System Navy, the Caliphate space defense force.
- the Zanzibar Liberation Front, a rebel force fighting the Caliphate.