Masada colonization

This kinda goes out to people who have an idea about population growth and the likes.

We know that the Masada colony was founded by less than 50,000 people in the 14th Century PD. (HH2 said that I think) Would that be a significant enough population to colonize a planet to a point that you could build a space navy a few hundred years later? Especially considering how anti-tech they were?

I'm asking because I remember an episode of the reimagined BattleStar Galactica series where they did some calculations and realized that even if they found a new planet, their numbers where to small to build up a lasting human population.

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