DuQuesne may refer to:
- DuQuesne Base, a People's Navy base on Enki in the Barnett System.
- DuQuesne-class, a Havenite class of superdreadnoughts.
- DuQuesne, a Legislaturist and the creator of the DuQuesne Plan.
- DuQuesne Ocean, a sea on the prison planet Hades.
- DuQuesne Plan, the concept for the creation and expansion of the People's Republic of Haven.
- DuQuesne Station, located at Enki
- DuQuesne Tower, a Dolist habitat on the planet Haven.