The Dempsey Cartel was a large Manticoran business concern, second only to the Hauptman Cartel on the Kingdom Five Hundred.

It was originally founded along with the Dempsey's Bar restaurant chain. (HH5)

By the early 1900s PD, Erika Dempsey was its the owner and chief operating officer. The cartel suffered great losses when the People's Navy began to raid commerce in the Silesian Confederacy, and urged the Manticoran government to do something about it. (HH6)